Serine hydrolase-like protein 2 (SERHL2)
Homo sapiens — UniProt Q9H4I8
Data last refreshed: (UniProt release unknown)
Key facts
Serine hydrolase-like protein 2 (SERHL2) is a protein from Homo sapiens identified by UniProt accession Q9H4I8, 314 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9H4I8; gene symbol SERHL2.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, reticulocyte measurement and apolipoprotein A 1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine hydrolase-like protein 2 |
|---|---|
| UniProt accession | Q9H4I8 |
| Gene | SERHL2 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.10
- reticulocyte measurement · score 0.09
- apolipoprotein A 1 measurement · score 0.05
- mean platelet volume · score 0.05
- calcium measurement · score 0.05
- metabolite measurement · score 0.02
- gastric carcinoma · score 0.01
- psoriasis · score 0.01
- Norrie disease · score 0.00
- breast ductal carcinoma in situ · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4I8-F1 | alphafold | PREDICTED | 90.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4I8.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERHL2?
The strongest Open Targets associations for SERHL2 are self reported educational attainment, reticulocyte measurement, apolipoprotein A 1 measurement, mean platelet volume and calcium measurement.
How long is the SERHL2 protein?
The Homo sapiens SERHL2 protein (UniProt Q9H4I8) is 314 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4I8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4I8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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