Oxysterol-binding protein-related protein 3 (OSBPL3)
Homo sapiens — UniProt Q9H4L5
Data last refreshed: (UniProt release unknown)
Key facts
Oxysterol-binding protein-related protein 3 (OSBPL3) is a protein from Homo sapiens identified by UniProt accession Q9H4L5, 887 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9H4L5; gene symbol OSBPL3.
- Organism: Homo sapiens.
- Length: 887 amino acids.
- Top disease associations (Open Targets): mathematical ability, self reported educational attainment and respiratory system disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxysterol-binding protein-related protein 3 |
|---|---|
| UniProt accession | Q9H4L5 |
| Gene | OSBPL3 |
| Organism | Homo sapiens |
| Length | 887 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.42
- self reported educational attainment · score 0.32
- respiratory system disease · score 0.31
- PHF-tau measurement · score 0.19
- response to vaccine · score 0.16
- lymphocyte count · score 0.16
- neoplasm · score 0.11
- bipolar disorder · score 0.10
- unipolar depression · score 0.10
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4L5-F1 | alphafold | PREDICTED | 71.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4L5.
Amino-acid sequence (887 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSBPL3?
The strongest Open Targets associations for OSBPL3 are mathematical ability, self reported educational attainment, respiratory system disease, PHF-tau measurement and response to vaccine.
How long is the OSBPL3 protein?
The Homo sapiens OSBPL3 protein (UniProt Q9H4L5) is 887 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4L5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4L5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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