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F-box only protein 44 (FBXO44)

Homo sapiens — UniProt Q9H4M3

Gene: FBXO44Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

F-box only protein 44 (FBXO44) is a protein from Homo sapiens identified by UniProt accession Q9H4M3, 255 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

  • UniProt accession: Q9H4M3; gene symbol FBXO44.
  • Organism: Homo sapiens.
  • Length: 255 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, periodontal disorder and hip bone size.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameF-box only protein 44
UniProt accessionQ9H4M3
GeneFBXO44
OrganismHomo sapiens
Length255 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (14)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.19
  • periodontal disorder · score 0.16
  • hip bone size · score 0.11
  • hip bone mineral density · score 0.08
  • neoplasm · score 0.05
  • basophil percentage of leukocytes · score 0.04
  • basophil count · score 0.04
  • cancer · score 0.02
  • lung adenocarcinoma · score 0.01
  • atherosclerosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H4M3-F1alphafoldPREDICTED92.41—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4M3.

Amino-acid sequence (255 residues)

MAVGNINELP ENILLELFTH VPARQLLLNC RLVCSLWRDL IDLVTLWKRK CLREGFITED WDQPVADWKI FYFLRSLHRN LLHNPCAEEG FEFWSLDVNG GDEWKVEDLS RDQRKEFPND QVKKYFVTSY YTCLKSQVVD LKAEGYWEEL MDTTRPDIEV KDWFAARPDC GSKYQLCVQL LSSAHAPLGT FQPDPATIQQ KSDAKWREVS HTFSNYPPGV RYIWFQHGGV DTHYWAGWYG PRVTNSSITI GPPLP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FBXO44?

The strongest Open Targets associations for FBXO44 are blood protein measurement, periodontal disorder, hip bone size, hip bone mineral density and neoplasm.

How long is the FBXO44 protein?

The Homo sapiens FBXO44 protein (UniProt Q9H4M3) is 255 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H4M3
GeneFBXO44
OrganismHomo sapiens
Length255
Binders0
Diseases14
View on UniProt