EH domain-containing protein 1 (EHD1)
Homo sapiens — UniProt Q9H4M9
Data last refreshed: (UniProt release unknown)
Key facts
EH domain-containing protein 1 (EHD1) is a protein from Homo sapiens identified by UniProt accession Q9H4M9, 534 residues long. MolForge cross-references it against 0 known binders and 187 disease associations.
- UniProt accession: Q9H4M9; gene symbol EHD1.
- Organism: Homo sapiens.
- Length: 534 amino acids.
- Top disease associations (Open Targets): ovarian cancer, breast adenocarcinoma and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EH domain-containing protein 1 |
|---|---|
| UniProt accession | Q9H4M9 |
| Gene | EHD1 |
| Organism | Homo sapiens |
| Length | 534 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (187)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- non-small cell lung carcinoma · score 0.11
- neoplasm · score 0.10
- adolescent idiopathic scoliosis · score 0.08
- lung adenocarcinoma · score 0.07
- azoospermia · score 0.07
- partial chromosome Y deletion · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.06
- spermatogenic failures 50 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4M9-F1 | alphafold | PREDICTED | 89.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4M9.
Amino-acid sequence (534 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EHD1?
The strongest Open Targets associations for EHD1 are ovarian cancer, breast adenocarcinoma, non-small cell lung carcinoma, neoplasm and adolescent idiopathic scoliosis.
How long is the EHD1 protein?
The Homo sapiens EHD1 protein (UniProt Q9H4M9) is 534 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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