PR domain zinc finger protein 13 (PRDM13)
Homo sapiens — UniProt Q9H4Q3
Data last refreshed: (UniProt release unknown)
Key facts
PR domain zinc finger protein 13 (PRDM13) is a protein from Homo sapiens identified by UniProt accession Q9H4Q3, 707 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.
- UniProt accession: Q9H4Q3; gene symbol PRDM13.
- Organism: Homo sapiens.
- Length: 707 amino acids.
- Top disease associations (Open Targets): cerebellar dysfunction, impaired intellectual development, and hypogonadotropic hypogonadism, pontocerebellar hypoplasia, IIA 17 and North Carolina macular dystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PR domain zinc finger protein 13 |
|---|---|
| UniProt accession | Q9H4Q3 |
| Gene | PRDM13 |
| Organism | Homo sapiens |
| Length | 707 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (144)
Diseases linked to this target (Open Targets).
- cerebellar dysfunction, impaired intellectual development, and hypogonadotropic hypogonadism · score 0.64
- pontocerebellar hypoplasia, IIA 17 · score 0.62
- North Carolina macular dystrophy · score 0.48
- congenital hypogonadotropic hypogonadism · score 0.42
- genetic disorder · score 0.41
- testosterone measurement · score 0.38
- age at menarche · score 0.37
- neurodegenerative disease · score 0.37
- enuresis · score 0.36
- body height · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4Q3-F1 | alphafold | PREDICTED | 52.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4Q3.
Amino-acid sequence (707 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM13?
The strongest Open Targets associations for PRDM13 are cerebellar dysfunction, impaired intellectual development, and hypogonadotropic hypogonadism, pontocerebellar hypoplasia, IIA 17, North Carolina macular dystrophy, congenital hypogonadotropic hypogonadism and genetic disorder.
How long is the PRDM13 protein?
The Homo sapiens PRDM13 protein (UniProt Q9H4Q3) is 707 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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