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Zinc finger and SCAN domain-containing protein 16 (ZSCAN16)

Homo sapiens — UniProt Q9H4T2

Gene: ZSCAN16Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger and SCAN domain-containing protein 16 (ZSCAN16) is a protein from Homo sapiens identified by UniProt accession Q9H4T2, 348 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

  • UniProt accession: Q9H4T2; gene symbol ZSCAN16.
  • Organism: Homo sapiens.
  • Length: 348 amino acids.
  • Top disease associations (Open Targets): type 1 diabetes mellitus, hypothyroidism and brain measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger and SCAN domain-containing protein 16
UniProt accessionQ9H4T2
GeneZSCAN16
OrganismHomo sapiens
Length348 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (79)

Diseases linked to this target (Open Targets).

  • type 1 diabetes mellitus · score 0.41
  • hypothyroidism · score 0.15
  • brain measurement · score 0.12
  • lean body mass · score 0.10
  • complement factor B measurement · score 0.09
  • hepatocellular carcinoma · score 0.08
  • unipolar depression · score 0.08
  • melanoma · score 0.08
  • Red cell distribution width · score 0.07
  • liver iron measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H4T2-F1alphafoldPREDICTED66.84—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4T2.

Amino-acid sequence (348 residues)

MTTALEPEDQ KGLLIIKAED HYWGQDSSSQ KCSPHRRELY RQHFRKLCYQ DAPGPREALT QLWELCRQWL RPECHTKEQI LDLLVLEQFL SILPKDLQAW VRAHHPETGE EAVTVLEDLE RELDEPGKQV PGNSERRDIL MDKLAPLGRP YESLTVQLHP KKTQLEQEAG KPQRNGDKTR TKNEELFQKE DMPKDKEFLG EINDRLNKDT PQHPKSKDII ENEGRSEWQQ RERRRYKCDE CGKSFSHSSD LSKHRRTHTG EKPYKCDECG KAFIQRSHLI GHHRVHTGVK PYKCKECGKD FSGRTGLIQH QRIHTGEKPY ECDECGRPFR VSSALIRHQR IHTANKLY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZSCAN16?

The strongest Open Targets associations for ZSCAN16 are type 1 diabetes mellitus, hypothyroidism, brain measurement, lean body mass and complement factor B measurement.

How long is the ZSCAN16 protein?

The Homo sapiens ZSCAN16 protein (UniProt Q9H4T2) is 348 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H4T2
GeneZSCAN16
OrganismHomo sapiens
Length348
Binders0
Diseases79
View on UniProt