Glutathione S-transferase omega-2 (GSTO2)
Homo sapiens — UniProt Q9H4Y5
Data last refreshed: (UniProt release unknown)
Key facts
Glutathione S-transferase omega-2 (GSTO2) is a protein from Homo sapiens identified by UniProt accession Q9H4Y5, 243 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.
- UniProt accession: Q9H4Y5; gene symbol GSTO2.
- Organism: Homo sapiens.
- Length: 243 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, protein measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutathione S-transferase omega-2 |
|---|---|
| UniProt accession | Q9H4Y5 |
| Gene | GSTO2 |
| Organism | Homo sapiens |
| Length | 243 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (103)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- protein measurement · score 0.23
- mathematical ability · score 0.22
- glioblastoma multiforme · score 0.16
- blood protein measurement · score 0.14
- smoking status measurement · score 0.10
- neoplasm · score 0.06
- COVID-19 · score 0.05
- chronic kidney disease · score 0.05
- laryngeal squamous cell carcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H4Y5-F1 | alphafold | PREDICTED | 97.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H4Y5.
Amino-acid sequence (243 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GSTO2?
The strongest Open Targets associations for GSTO2 are neurodegenerative disease, protein measurement, mathematical ability, glioblastoma multiforme and blood protein measurement.
How long is the GSTO2 protein?
The Homo sapiens GSTO2 protein (UniProt Q9H4Y5) is 243 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H4Y5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H4Y5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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