ESF1 homolog (ESF1)
Homo sapiens — UniProt Q9H501
Data last refreshed: (UniProt release unknown)
Key facts
ESF1 homolog (ESF1) is a protein from Homo sapiens identified by UniProt accession Q9H501, 851 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9H501; gene symbol ESF1.
- Organism: Homo sapiens.
- Length: 851 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, drug use measurement and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ESF1 homolog |
|---|---|
| UniProt accession | Q9H501 |
| Gene | ESF1 |
| Organism | Homo sapiens |
| Length | 851 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- drug use measurement · score 0.22
- PHF-tau measurement · score 0.19
- cardiovascular disease · score 0.09
- Obesity · score 0.02
- injury · score 0.01
- neoplasm · score 0.00
- COVID-19 · score 0.00
- Henipavirus infectious disease · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H501-F1 | alphafold | PREDICTED | 64.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H501.
Amino-acid sequence (851 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ESF1?
The strongest Open Targets associations for ESF1 are neurodegenerative disease, drug use measurement, PHF-tau measurement, cardiovascular disease and Obesity.
How long is the ESF1 protein?
The Homo sapiens ESF1 protein (UniProt Q9H501) is 851 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H501 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H501 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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