Zinc finger protein 644 (ZNF644)
Homo sapiens — UniProt Q9H582
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 644 (ZNF644) is a protein from Homo sapiens identified by UniProt accession Q9H582, 1327 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q9H582; gene symbol ZNF644.
- Organism: Homo sapiens.
- Length: 1327 amino acids.
- Top disease associations (Open Targets): Myopia, IGF-1 measurement and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 644 |
|---|---|
| UniProt accession | Q9H582 |
| Gene | ZNF644 |
| Organism | Homo sapiens |
| Length | 1327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- Myopia · score 0.73
- IGF-1 measurement · score 0.30
- lymphocyte count · score 0.29
- C-reactive protein measurement · score 0.27
- insulin like growth factor measurement · score 0.26
- sex hormone-binding globulin measurement · score 0.25
- platelet count · score 0.25
- calcium measurement · score 0.24
- drug use measurement · score 0.24
- alkaline phosphatase measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H582-F1 | alphafold | PREDICTED | 45.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H582.
Amino-acid sequence (1327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF644?
The strongest Open Targets associations for ZNF644 are Myopia, IGF-1 measurement, lymphocyte count, C-reactive protein measurement and insulin like growth factor measurement.
How long is the ZNF644 protein?
The Homo sapiens ZNF644 protein (UniProt Q9H582) is 1327 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H582 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H582 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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