Vesicular inhibitory amino acid transporter (SLC32A1)
Homo sapiens — UniProt Q9H598
Data last refreshed: (UniProt release unknown)
Key facts
Vesicular inhibitory amino acid transporter (SLC32A1) is a protein from Homo sapiens identified by UniProt accession Q9H598, 525 residues long. MolForge cross-references it against 0 known binders and 161 disease associations.
- UniProt accession: Q9H598; gene symbol SLC32A1.
- Organism: Homo sapiens.
- Length: 525 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): developmental and epileptic encephalopathy, generalized epilepsy with febrile seizures plus and Seizure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicular inhibitory amino acid transporter |
|---|---|
| UniProt accession | Q9H598 |
| Gene | SLC32A1 |
| Organism | Homo sapiens |
| Length | 525 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (161)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy · score 0.42
- generalized epilepsy with febrile seizures plus · score 0.38
- Seizure · score 0.37
- Intellectual disability · score 0.37
- schizophrenia · score 0.29
- neurodegenerative disease · score 0.26
- neuroinflammatory disorder · score 0.25
- BMI-adjusted leptin measurement · score 0.23
- genetic disorder · score 0.19
- cutaneous melanoma · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H598-F1 | alphafold | PREDICTED | 78.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H598.
Amino-acid sequence (525 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC32A1?
The strongest Open Targets associations for SLC32A1 are developmental and epileptic encephalopathy, generalized epilepsy with febrile seizures plus, Seizure, Intellectual disability and schizophrenia.
How long is the SLC32A1 protein?
The Homo sapiens SLC32A1 protein (UniProt Q9H598) is 525 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H598 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H598 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.