Cilia- and flagella-associated protein 68 (CFAP68)
Homo sapiens — UniProt Q9H5F2
Data last refreshed: (UniProt release unknown)
Key facts
Cilia- and flagella-associated protein 68 (CFAP68) is a protein from Homo sapiens identified by UniProt accession Q9H5F2, 150 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9H5F2; gene symbol CFAP68.
- Organism: Homo sapiens.
- Length: 150 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, PR interval and cardiovascular disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cilia- and flagella-associated protein 68 |
|---|---|
| UniProt accession | Q9H5F2 |
| Gene | CFAP68 |
| Organism | Homo sapiens |
| Length | 150 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.25
- PR interval · score 0.20
- cardiovascular disease · score 0.19
- birth weight · score 0.17
- systolic blood pressure · score 0.17
- hypertension · score 0.10
- mean platelet volume · score 0.08
- Red cell distribution width · score 0.08
- uric acid measurement · score 0.06
- triglyceride measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5F2-F1 | alphafold | PREDICTED | 69.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5F2.
Amino-acid sequence (150 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CFAP68?
The strongest Open Targets associations for CFAP68 are diastolic blood pressure, PR interval, cardiovascular disease, birth weight and systolic blood pressure.
How long is the CFAP68 protein?
The Homo sapiens CFAP68 protein (UniProt Q9H5F2) is 150 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5F2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5F2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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