Zinc finger protein 768 (ZNF768)
Homo sapiens — UniProt Q9H5H4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 768 (ZNF768) is a protein from Homo sapiens identified by UniProt accession Q9H5H4, 540 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9H5H4; gene symbol ZNF768.
- Organism: Homo sapiens.
- Length: 540 amino acids.
- Top disease associations (Open Targets): serum gamma-glutamyl transferase measurement, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 768 |
|---|---|
| UniProt accession | Q9H5H4 |
| Gene | ZNF768 |
| Organism | Homo sapiens |
| Length | 540 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.25
- cancer · score 0.09
- neoplasm · score 0.08
- lung adenocarcinoma · score 0.08
- erythrocyte count · score 0.02
- Neoplasm of the lung · score 0.01
- non-small cell lung carcinoma · score 0.01
- chronic kidney disease · score 0.01
- pancreatic adenocarcinoma · score 0.01
- Thymoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5H4-F1 | alphafold | PREDICTED | 64.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5H4.
Amino-acid sequence (540 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF768?
The strongest Open Targets associations for ZNF768 are serum gamma-glutamyl transferase measurement, cancer, neoplasm, lung adenocarcinoma and erythrocyte count.
How long is the ZNF768 protein?
The Homo sapiens ZNF768 protein (UniProt Q9H5H4) is 540 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5H4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5H4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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