Histone-lysine N-methyltransferase SUV39H2 (SUV39H2)
Homo sapiens — UniProt Q9H5I1
Data last refreshed: (UniProt release unknown)
Key facts
Histone-lysine N-methyltransferase SUV39H2 (SUV39H2) is a protein from Homo sapiens identified by UniProt accession Q9H5I1, 410 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q9H5I1; gene symbol SUV39H2.
- Organism: Homo sapiens.
- Length: 410 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone-lysine N-methyltransferase SUV39H2 |
|---|---|
| UniProt accession | Q9H5I1 |
| Gene | SUV39H2 |
| Organism | Homo sapiens |
| Length | 410 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- blood protein measurement · score 0.27
- lymphocyte count · score 0.15
- protein measurement · score 0.14
- clear cell renal carcinoma · score 0.10
- lymphocyte percentage of leukocytes · score 0.09
- acute lymphoblastic leukemia · score 0.09
- osteosarcoma · score 0.06
- reticulum cell sarcoma · score 0.06
- Ewing sarcoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5I1-F1 | alphafold | PREDICTED | 89.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5I1.
Amino-acid sequence (410 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUV39H2?
The strongest Open Targets associations for SUV39H2 are neurodegenerative disease, blood protein measurement, lymphocyte count, protein measurement and clear cell renal carcinoma.
How long is the SUV39H2 protein?
The Homo sapiens SUV39H2 protein (UniProt Q9H5I1) is 410 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5I1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5I1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.