Zinc finger and BTB domain-containing protein 3 (ZBTB3)
Homo sapiens — UniProt Q9H5J0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 3 (ZBTB3) is a protein from Homo sapiens identified by UniProt accession Q9H5J0, 574 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9H5J0; gene symbol ZBTB3.
- Organism: Homo sapiens.
- Length: 574 amino acids.
- Top disease associations (Open Targets): cancer, smoking status measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 3 |
|---|---|
| UniProt accession | Q9H5J0 |
| Gene | ZBTB3 |
| Organism | Homo sapiens |
| Length | 574 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- cancer · score 0.07
- smoking status measurement · score 0.05
- urate measurement · score 0.04
- neoplasm · score 0.02
- esophageal squamous cell carcinoma · score 0.01
- breast carcinoma · score 0.01
- melanoma · score 0.01
- Hepatoblastoma · score 0.01
- small cell lung carcinoma · score 0.01
- systemic juvenile idiopathic arthritis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5J0-F1 | alphafold | PREDICTED | 54.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5J0.
Amino-acid sequence (574 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB3?
The strongest Open Targets associations for ZBTB3 are cancer, smoking status measurement, urate measurement, neoplasm and esophageal squamous cell carcinoma.
How long is the ZBTB3 protein?
The Homo sapiens ZBTB3 protein (UniProt Q9H5J0) is 574 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5J0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5J0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.