Very long chain fatty acid elongase 6 (ELOVL6)
Homo sapiens — UniProt Q9H5J4
Data last refreshed: (UniProt release unknown)
Key facts
Very long chain fatty acid elongase 6 (ELOVL6) is a protein from Homo sapiens identified by UniProt accession Q9H5J4, 265 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.
- UniProt accession: Q9H5J4; gene symbol ELOVL6.
- Organism: Homo sapiens.
- Length: 265 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, fibromyalgia and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Very long chain fatty acid elongase 6 |
|---|---|
| UniProt accession | Q9H5J4 |
| Gene | ELOVL6 |
| Organism | Homo sapiens |
| Length | 265 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (167)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.49
- fibromyalgia · score 0.23
- platelet count · score 0.12
- neoplasm · score 0.08
- lung adenocarcinoma · score 0.08
- hepatocellular carcinoma · score 0.07
- myeloid white cell count · score 0.07
- oral squamous cell carcinoma · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.05
- hypertriglyceridemia 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5J4-F1 | alphafold | PREDICTED | 92.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5J4.
Amino-acid sequence (265 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELOVL6?
The strongest Open Targets associations for ELOVL6 are alkaline phosphatase measurement, fibromyalgia, platelet count, neoplasm and lung adenocarcinoma.
How long is the ELOVL6 protein?
The Homo sapiens ELOVL6 protein (UniProt Q9H5J4) is 265 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5J4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5J4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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