TATA box-binding protein-associated factor RNA polymerase I subunit D (TAF1D)
Homo sapiens — UniProt Q9H5J8
Data last refreshed: (UniProt release unknown)
Key facts
TATA box-binding protein-associated factor RNA polymerase I subunit D (TAF1D) is a protein from Homo sapiens identified by UniProt accession Q9H5J8, 278 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9H5J8; gene symbol TAF1D.
- Organism: Homo sapiens.
- Length: 278 amino acids.
- Top disease associations (Open Targets): protein measurement, BMI-adjusted waist circumference and response to selective serotonin reuptake inhibitor.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TATA box-binding protein-associated factor RNA polymerase I subunit D |
|---|---|
| UniProt accession | Q9H5J8 |
| Gene | TAF1D |
| Organism | Homo sapiens |
| Length | 278 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.16
- BMI-adjusted waist circumference · score 0.06
- response to selective serotonin reuptake inhibitor · score 0.05
- cancer · score 0.05
- neoplasm · score 0.04
- smoking status measurement · score 0.04
- neutrophil count · score 0.04
- myeloid white cell count · score 0.03
- mean reticulocyte volume · score 0.03
- adolescent idiopathic scoliosis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5J8-F1 | alphafold | PREDICTED | 62.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5J8.
Amino-acid sequence (278 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAF1D?
The strongest Open Targets associations for TAF1D are protein measurement, BMI-adjusted waist circumference, response to selective serotonin reuptake inhibitor, cancer and neoplasm.
How long is the TAF1D protein?
The Homo sapiens TAF1D protein (UniProt Q9H5J8) is 278 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5J8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5J8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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