PDZ domain-containing protein 7 (PDZD7)
Homo sapiens — UniProt Q9H5P4
Data last refreshed: (UniProt release unknown)
Key facts
PDZ domain-containing protein 7 (PDZD7) is a protein from Homo sapiens identified by UniProt accession Q9H5P4, 1033 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9H5P4; gene symbol PDZD7.
- Organism: Homo sapiens.
- Length: 1033 amino acids.
- Top disease associations (Open Targets): hearing loss, autosomal recessive 57, Usher syndrome type 2 and Usher syndrome type 2A.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PDZ domain-containing protein 7 |
|---|---|
| UniProt accession | Q9H5P4 |
| Gene | PDZD7 |
| Organism | Homo sapiens |
| Length | 1033 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- hearing loss, autosomal recessive 57 · score 0.74
- Usher syndrome type 2 · score 0.55
- Usher syndrome type 2A · score 0.55
- Usher syndrome · score 0.51
- genetic disorder · score 0.41
- hearing loss, autosomal recessive · score 0.41
- autosomal dominant nonsyndromic hearing loss · score 0.28
- Rare genetic deafness · score 0.28
- ear malformation · score 0.27
- Abnormality of the ear · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5P4-F1 | alphafold | PREDICTED | 56.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5P4.
Amino-acid sequence (1033 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDZD7?
The strongest Open Targets associations for PDZD7 are hearing loss, autosomal recessive 57, Usher syndrome type 2, Usher syndrome type 2A, Usher syndrome and genetic disorder.
How long is the PDZD7 protein?
The Homo sapiens PDZD7 protein (UniProt Q9H5P4) is 1033 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5P4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5P4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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