rRNA N(6)-adenosine-methyltransferase ZCCHC4 (ZCCHC4)
Homo sapiens — UniProt Q9H5U6
Data last refreshed: (UniProt release unknown)
Key facts
rRNA N(6)-adenosine-methyltransferase ZCCHC4 (ZCCHC4) is a protein from Homo sapiens identified by UniProt accession Q9H5U6, 513 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9H5U6; gene symbol ZCCHC4.
- Organism: Homo sapiens.
- Length: 513 amino acids.
- Top disease associations (Open Targets): body mass index, fat body mass and gut microbiome measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | rRNA N(6)-adenosine-methyltransferase ZCCHC4 |
|---|---|
| UniProt accession | Q9H5U6 |
| Gene | ZCCHC4 |
| Organism | Homo sapiens |
| Length | 513 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- body mass index · score 0.18
- fat body mass · score 0.15
- gut microbiome measurement · score 0.14
- body fat percentage · score 0.14
- multisite chronic pain · score 0.14
- metabolite measurement · score 0.09
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.08
- lean body mass · score 0.07
- cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5U6-F1 | alphafold | PREDICTED | 82.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5U6.
Amino-acid sequence (513 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZCCHC4?
The strongest Open Targets associations for ZCCHC4 are body mass index, fat body mass, gut microbiome measurement, body fat percentage and multisite chronic pain.
How long is the ZCCHC4 protein?
The Homo sapiens ZCCHC4 protein (UniProt Q9H5U6) is 513 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5U6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5U6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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