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CUB domain-containing protein 1 (CDCP1)

Homo sapiens — UniProt Q9H5V8

Gene: CDCP1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

CUB domain-containing protein 1 (CDCP1) is a protein from Homo sapiens identified by UniProt accession Q9H5V8, 836 residues long. MolForge cross-references it against 0 known binders and 147 disease associations.

  • UniProt accession: Q9H5V8; gene symbol CDCP1.
  • Organism: Homo sapiens.
  • Length: 836 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, macula measurement and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCUB domain-containing protein 1
UniProt accessionQ9H5V8
GeneCDCP1
OrganismHomo sapiens
Length836 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (147)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.37
  • macula measurement · score 0.30
  • body mass index · score 0.26
  • neoplasm · score 0.11
  • myoepithelial tumor · score 0.11
  • cancer · score 0.10
  • triple-negative breast cancer · score 0.10
  • ulcerative colitis · score 0.09
  • acute myeloid leukemia · score 0.09
  • urinary bladder carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H5V8-F1alphafoldPREDICTED77.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5V8.

Amino-acid sequence (836 residues)

MAGLNCGVSI ALLGVLLLGA ARLPRGAEAF EIALPRESNI TVLIKLGTPT LLAKPCYIVI SKRHITMLSI KSGERIVFTF SCQSPENHFV IEIQKNIDCM SGPCPFGEVQ LQPSTSLLPT LNRTFIWDVK AHKSIGLELQ FSIPRLRQIG PGESCPDGVT HSISGRIDAT VVRIGTFCSN GTVSRIKMQE GVKMALHLPW FHPRNVSGFS IANRSSIKRL CIIESVFEGE GSATLMSANY PEGFPEDELM TWQFVVPAHL RASVSFLNFN LSNCERKEER VEYYIPGSTT NPEVFKLEDK QPGNMAGNFN LSLQGCDQDA QSPGILRLQF QVLVQHPQNE SNKIYVVDLS NERAMSLTIE PRPVKQSRKF VPGCFVCLES RTCSSNLTLT SGSKHKISFL CDDLTRLWMN VEKTISCTDH RYCQRKSYSL QVPSDILHLP VELHDFSWKL LVPKDRLSLV LVPAQKLQQH THEKPCNTSF SYLVASAIPS QDLYFGSFCP GGSIKQIQVK QNISVTLRTF APSFQQEASR QGLTVSFIPY FKEEGVFTVT PDTKSKVYLR TPNWDRGLPS LTSVSWNISV PRDQVACLTF FKERSGVVCQ TGRAFMIIQE QRTRAEEIFS LDEDVLPKPS FHHHSFWVNI SNCSPTSGKQ LDLLFSVTLT PRTVDLTVIL IAAVGGGVLL LSALGLIICC VKKKKKKTNK GPAVGIYNDN INTEMPRQPK KFQKGRKDND SHVYAVIEDT MVYGHLLQDS SGSFLQPEVD TYRPFQGTMG VCPPSPPTIC SRAPTAKLAT EEPPPRSPPE SESEPYTFSH PNNGDVSSKD TDIPLLNTQE PMEPAE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CDCP1?

The strongest Open Targets associations for CDCP1 are blood protein measurement, macula measurement, body mass index, neoplasm and myoepithelial tumor.

How long is the CDCP1 protein?

The Homo sapiens CDCP1 protein (UniProt Q9H5V8) is 836 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H5V8
GeneCDCP1
OrganismHomo sapiens
Length836
Binders0
Diseases147
View on UniProt