STING ER exit protein (STEEP1)
Homo sapiens — UniProt Q9H5V9
Data last refreshed: (UniProt release unknown)
Key facts
STING ER exit protein (STEEP1) is a protein from Homo sapiens identified by UniProt accession Q9H5V9, 222 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9H5V9; gene symbol STEEP1.
- Organism: Homo sapiens.
- Length: 222 amino acids.
- Top disease associations (Open Targets): X-linked non-syndromic intellectual disability, triple-negative breast cancer and breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | STING ER exit protein |
|---|---|
| UniProt accession | Q9H5V9 |
| Gene | STEEP1 |
| Organism | Homo sapiens |
| Length | 222 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- X-linked non-syndromic intellectual disability · score 0.63
- triple-negative breast cancer · score 0.07
- breast cancer · score 0.06
- Intellectual disability · score 0.01
- neoplasm · score 0.01
- cancer · score 0.01
- X-linked intellectual disability · score 0.01
- Thymoma · score 0.01
- Systemic lupus erythematosus · score 0.01
- STING-associated vasculopathy with onset in infancy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5V9-F1 | alphafold | PREDICTED | 76.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5V9.
Amino-acid sequence (222 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STEEP1?
The strongest Open Targets associations for STEEP1 are X-linked non-syndromic intellectual disability, triple-negative breast cancer, breast cancer, Intellectual disability and neoplasm.
How long is the STEEP1 protein?
The Homo sapiens STEEP1 protein (UniProt Q9H5V9) is 222 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5V9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5V9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.