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SLIT and NTRK-like protein 6 (SLITRK6)

Homo sapiens — UniProt Q9H5Y7

Gene: SLITRK6Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

SLIT and NTRK-like protein 6 (SLITRK6) is a protein from Homo sapiens identified by UniProt accession Q9H5Y7, 841 residues long. MolForge cross-references it against 0 known binders and 126 disease associations.

  • UniProt accession: Q9H5Y7; gene symbol SLITRK6.
  • Organism: Homo sapiens.
  • Length: 841 amino acids.
  • Top disease associations (Open Targets): high myopia-sensorineural deafness syndrome, body fat percentage and fat body mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSLIT and NTRK-like protein 6
UniProt accessionQ9H5Y7
GeneSLITRK6
OrganismHomo sapiens
Length841 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (126)

Diseases linked to this target (Open Targets).

  • high myopia-sensorineural deafness syndrome · score 0.69
  • body fat percentage · score 0.47
  • fat body mass · score 0.42
  • body mass index · score 0.39
  • hearing loss, autosomal recessive · score 0.37
  • Global developmental delay · score 0.34
  • C-reactive protein measurement · score 0.31
  • lean body mass · score 0.31
  • body height · score 0.30
  • lifestyle measurement · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H5Y7-F1alphafoldPREDICTED67.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5Y7.

Amino-acid sequence (841 residues)

MKLWIHLFYS SLLACISLHS QTPVLSSRGS CDSLCNCEEK DGTMLINCEA KGIKMVSEIS VPPSRPFQLS LLNNGLTMLH TNDFSGLTNA ISIHLGFNNI ADIEIGAFNG LGLLKQLHIN HNSLEILKED TFHGLENLEF LQADNNFITV IEPSAFSKLN RLKVLILNDN AIESLPPNIF RFVPLTHLDL RGNQLQTLPY VGFLEHIGRI LDLQLEDNKW ACNCDLLQLK TWLENMPPQS IIGDVVCNSP PFFKGSILSR LKKESICPTP PVYEEHEDPS GSLHLAATSS INDSRMSTKT TSILKLPTKA PGLIPYITKP STQLPGPYCP IPCNCKVLSP SGLLIHCQER NIESLSDLRP PPQNPRKLIL AGNIIHSLMK SDLVEYFTLE MLHLGNNRIE VLEEGSFMNL TRLQKLYLNG NHLTKLSKGM FLGLHNLEYL YLEYNAIKEI LPGTFNPMPK LKVLYLNNNL LQVLPPHIFS GVPLTKVNLK TNQFTHLPVS NILDDLDLLT QIDLEDNPWD CSCDLVGLQQ WIQKLSKNTV TDDILCTSPG HLDKKELKAL NSEILCPGLV NNPSMPTQTS YLMVTTPATT TNTADTILRS LTDAVPLSVL ILGLLIMFIT IVFCAAGIVV LVLHRRRRYK KKQVDEQMRD NSPVHLQYSM YGHKTTHHTT ERPSASLYEQ HMVSPMVHVY RSPSFGPKHL EEEEERNEKE GSDAKHLQRS LLEQENHSPL TGSNMKYKTT NQSTEFLSFQ DASSLYRNIL EKERELQQLG ITEYLRKNIA QLQPDMEAHY PGAHEELKLM ETLMYSRPRK VLVEQTKNEY FELKANLHAE PDYLEVLEQQ T

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLITRK6?

The strongest Open Targets associations for SLITRK6 are high myopia-sensorineural deafness syndrome, body fat percentage, fat body mass, body mass index and hearing loss, autosomal recessive.

How long is the SLITRK6 protein?

The Homo sapiens SLITRK6 protein (UniProt Q9H5Y7) is 841 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H5Y7
GeneSLITRK6
OrganismHomo sapiens
Length841
Binders0
Diseases126
View on UniProt