Protein FAM124B (FAM124B)
Homo sapiens — UniProt Q9H5Z6
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM124B (FAM124B) is a protein from Homo sapiens identified by UniProt accession Q9H5Z6, 455 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9H5Z6; gene symbol FAM124B.
- Organism: Homo sapiens.
- Length: 455 amino acids.
- Top disease associations (Open Targets): cortical surface area measurement, body height and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM124B |
|---|---|
| UniProt accession | Q9H5Z6 |
| Gene | FAM124B |
| Organism | Homo sapiens |
| Length | 455 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.36
- body height · score 0.33
- brain measurement · score 0.24
- vital capacity · score 0.23
- BMI-adjusted waist circumference · score 0.22
- whole body water mass · score 0.21
- reticulocyte count · score 0.15
- appendicular lean mass · score 0.10
- BMI-adjusted waist-hip ratio · score 0.10
- platelet component distribution width · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H5Z6-F1 | alphafold | PREDICTED | 63.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H5Z6.
Amino-acid sequence (455 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM124B?
The strongest Open Targets associations for FAM124B are cortical surface area measurement, body height, brain measurement, vital capacity and BMI-adjusted waist circumference.
How long is the FAM124B protein?
The Homo sapiens FAM124B protein (UniProt Q9H5Z6) is 455 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H5Z6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H5Z6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.