Zinc finger protein 576 (ZNF576)
Homo sapiens — UniProt Q9H609
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 576 (ZNF576) is a protein from Homo sapiens identified by UniProt accession Q9H609, 170 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q9H609; gene symbol ZNF576.
- Organism: Homo sapiens.
- Length: 170 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, appendicular lean mass and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 576 |
|---|---|
| UniProt accession | Q9H609 |
| Gene | ZNF576 |
| Organism | Homo sapiens |
| Length | 170 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- appendicular lean mass · score 0.07
- low density lipoprotein cholesterol measurement · score 0.04
- forced expiratory volume · score 0.03
- metabolite measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H609-F1 | alphafold | PREDICTED | 74.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H609.
Amino-acid sequence (170 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF576?
The strongest Open Targets associations for ZNF576 are neurodegenerative disease, appendicular lean mass, low density lipoprotein cholesterol measurement, forced expiratory volume and metabolite measurement.
How long is the ZNF576 protein?
The Homo sapiens ZNF576 protein (UniProt Q9H609) is 170 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H609 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H609 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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