IGF-like family receptor 1 (IGFLR1)
Homo sapiens — UniProt Q9H665
Data last refreshed: (UniProt release unknown)
Key facts
IGF-like family receptor 1 (IGFLR1) is a protein from Homo sapiens identified by UniProt accession Q9H665, 355 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9H665; gene symbol IGFLR1.
- Organism: Homo sapiens.
- Length: 355 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, blood protein measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | IGF-like family receptor 1 |
|---|---|
| UniProt accession | Q9H665 |
| Gene | IGFLR1 |
| Organism | Homo sapiens |
| Length | 355 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.15
- blood protein measurement · score 0.11
- body height · score 0.08
- nonpapillary renal cell carcinoma · score 0.07
- mathematical ability · score 0.06
- age at first sexual intercourse measurement · score 0.06
- age at menarche · score 0.06
- self reported educational attainment · score 0.06
- white matter microstructure measurement · score 0.05
- brain measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H665-F1 | alphafold | PREDICTED | 71.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H665.
Amino-acid sequence (355 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGFLR1?
The strongest Open Targets associations for IGFLR1 are Red cell distribution width, blood protein measurement, body height, nonpapillary renal cell carcinoma and mathematical ability.
How long is the IGFLR1 protein?
The Homo sapiens IGFLR1 protein (UniProt Q9H665) is 355 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H665 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H665 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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