CST complex subunit STN1 (STN1)
Homo sapiens — UniProt Q9H668
Data last refreshed: (UniProt release unknown)
Key facts
CST complex subunit STN1 (STN1) is a protein from Homo sapiens identified by UniProt accession Q9H668, 368 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q9H668; gene symbol STN1.
- Organism: Homo sapiens.
- Length: 368 amino acids.
- Top disease associations (Open Targets): Coats plus syndrome, dyskeratosis congenita and telomere length.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CST complex subunit STN1 |
|---|---|
| UniProt accession | Q9H668 |
| Gene | STN1 |
| Organism | Homo sapiens |
| Length | 368 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- Coats plus syndrome · score 0.75
- dyskeratosis congenita · score 0.46
- telomere length · score 0.34
- systolic blood pressure · score 0.32
- sex hormone-binding globulin measurement · score 0.31
- mean corpuscular volume · score 0.31
- uterine fibroid · score 0.31
- cutaneous melanoma · score 0.30
- vital capacity · score 0.30
- erythrocyte count · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H668-F1 | alphafold | PREDICTED | 87.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H668.
Amino-acid sequence (368 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STN1?
The strongest Open Targets associations for STN1 are Coats plus syndrome, dyskeratosis congenita, telomere length, systolic blood pressure and sex hormone-binding globulin measurement.
How long is the STN1 protein?
The Homo sapiens STN1 protein (UniProt Q9H668) is 368 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H668 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H668 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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