Ankyrin repeat and SOCS box protein 7 (ASB7)
Homo sapiens — UniProt Q9H672
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 7 (ASB7) is a protein from Homo sapiens identified by UniProt accession Q9H672, 318 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9H672; gene symbol ASB7.
- Organism: Homo sapiens.
- Length: 318 amino acids.
- Top disease associations (Open Targets): chronotype measurement, cup-to-disc ratio measurement and optic cup area measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 7 |
|---|---|
| UniProt accession | Q9H672 |
| Gene | ASB7 |
| Organism | Homo sapiens |
| Length | 318 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.32
- cup-to-disc ratio measurement · score 0.23
- optic cup area measurement · score 0.21
- chin morphology measurement · score 0.18
- PHF-tau measurement · score 0.05
- drug use measurement · score 0.04
- Meacham syndrome · score 0.03
- neurofibrillary tangles measurement · score 0.02
- neoplasm · score 0.00
- Miyoshi myopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H672-F1 | alphafold | PREDICTED | 92.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H672.
Amino-acid sequence (318 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB7?
The strongest Open Targets associations for ASB7 are chronotype measurement, cup-to-disc ratio measurement, optic cup area measurement, chin morphology measurement and PHF-tau measurement.
How long is the ASB7 protein?
The Homo sapiens ASB7 protein (UniProt Q9H672) is 318 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H672 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H672 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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