Protein bicaudal C homolog 1 (BICC1)
Homo sapiens — UniProt Q9H694
Data last refreshed: (UniProt release unknown)
Key facts
Protein bicaudal C homolog 1 (BICC1) is a protein from Homo sapiens identified by UniProt accession Q9H694, 974 residues long. MolForge cross-references it against 0 known binders and 252 disease associations.
- UniProt accession: Q9H694; gene symbol BICC1.
- Organism: Homo sapiens.
- Length: 974 amino acids.
- Top disease associations (Open Targets): multicystic dysplastic kidney, urate measurement and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein bicaudal C homolog 1 |
|---|---|
| UniProt accession | Q9H694 |
| Gene | BICC1 |
| Organism | Homo sapiens |
| Length | 974 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (252)
Diseases linked to this target (Open Targets).
- multicystic dysplastic kidney · score 0.52
- urate measurement · score 0.50
- hemoglobin measurement · score 0.48
- heel bone mineral density · score 0.47
- refractive error · score 0.46
- hematocrit · score 0.45
- mean corpuscular volume · score 0.45
- refractive error measurement · score 0.43
- uric acid measurement · score 0.42
- systolic blood pressure · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H694-F1 | alphafold | PREDICTED | 59.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H694.
Amino-acid sequence (974 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BICC1?
The strongest Open Targets associations for BICC1 are multicystic dysplastic kidney, urate measurement, hemoglobin measurement, heel bone mineral density and refractive error.
How long is the BICC1 protein?
The Homo sapiens BICC1 protein (UniProt Q9H694) is 974 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H694 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H694 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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