Zinc finger protein 385D (ZNF385D)
Homo sapiens — UniProt Q9H6B1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 385D (ZNF385D) is a protein from Homo sapiens identified by UniProt accession Q9H6B1, 395 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9H6B1; gene symbol ZNF385D.
- Organism: Homo sapiens.
- Length: 395 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, PHF-tau measurement and acute graft vs. host disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 385D |
|---|---|
| UniProt accession | Q9H6B1 |
| Gene | ZNF385D |
| Organism | Homo sapiens |
| Length | 395 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.35
- PHF-tau measurement · score 0.34
- acute graft vs. host disease · score 0.31
- ceramide measurement · score 0.29
- arterial stiffness measurement · score 0.29
- seasonal gut microbiome measurement · score 0.28
- optic disc size measurement · score 0.27
- cognitive function measurement · score 0.27
- mathematical ability · score 0.26
- motion sickness · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6B1-F1 | alphafold | PREDICTED | 61.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6B1.
Amino-acid sequence (395 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF385D?
The strongest Open Targets associations for ZNF385D are self reported educational attainment, PHF-tau measurement, acute graft vs. host disease, ceramide measurement and arterial stiffness measurement.
How long is the ZNF385D protein?
The Homo sapiens ZNF385D protein (UniProt Q9H6B1) is 395 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6B1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6B1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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