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CXADR-like membrane protein (CLMP)

Homo sapiens — UniProt Q9H6B4

Gene: CLMPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

CXADR-like membrane protein (CLMP) is a protein from Homo sapiens identified by UniProt accession Q9H6B4, 373 residues long. MolForge cross-references it against 0 known binders and 127 disease associations.

  • UniProt accession: Q9H6B4; gene symbol CLMP.
  • Organism: Homo sapiens.
  • Length: 373 amino acids.
  • Top disease associations (Open Targets): congenital short bowel syndrome, congenital short bowel syndrome, autosomal recessive and intestinal pseudo-obstruction.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCXADR-like membrane protein
UniProt accessionQ9H6B4
GeneCLMP
OrganismHomo sapiens
Length373 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (127)

Diseases linked to this target (Open Targets).

  • congenital short bowel syndrome · score 0.67
  • congenital short bowel syndrome, autosomal recessive · score 0.59
  • intestinal pseudo-obstruction · score 0.44
  • blood protein measurement · score 0.43
  • heel bone mineral density · score 0.43
  • mean corpuscular hemoglobin concentration · score 0.36
  • mean corpuscular hemoglobin · score 0.33
  • hemorrhoid · score 0.32
  • Red cell distribution width · score 0.29
  • diet measurement · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H6B4-F1alphafoldPREDICTED76.77—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6B4.

Amino-acid sequence (373 residues)

MSLLLLLLLV SYYVGTLGTH TEIKRVAEEK VTLPCHHQLG LPEKDTLDIE WLLTDNEGNQ KVVITYSSRH VYNNLTEEQK GRVAFASNFL AGDASLQIEP LKPSDEGRYT CKVKNSGRYV WSHVILKVLV RPSKPKCELE GELTEGSDLT LQCESSSGTE PIVYYWQRIR EKEGEDERLP PKSRIDYNHP GRVLLQNLTM SYSGLYQCTA GNEAGKESCV VRVTVQYVQS IGMVAGAVTG IVAGALLIFL LVWLLIRRKD KERYEEEERP NEIREDAEAP KARLVKPSSS SSGSRSSRSG SSSTRSTANS ASRSQRTLST DAAPQPGLAT QAYSLVGPEV RGSEPKKVHH ANLTKAETTP SMIPSQSRAF QTV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CLMP?

The strongest Open Targets associations for CLMP are congenital short bowel syndrome, congenital short bowel syndrome, autosomal recessive, intestinal pseudo-obstruction, blood protein measurement and heel bone mineral density.

How long is the CLMP protein?

The Homo sapiens CLMP protein (UniProt Q9H6B4) is 373 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H6B4
GeneCLMP
OrganismHomo sapiens
Length373
Binders0
Diseases127
View on UniProt