Fibronectin type III domain-containing protein 4 (FNDC4)
Homo sapiens — UniProt Q9H6D8
Data last refreshed: (UniProt release unknown)
Key facts
Fibronectin type III domain-containing protein 4 (FNDC4) is a protein from Homo sapiens identified by UniProt accession Q9H6D8, 234 residues long. MolForge cross-references it against 0 known binders and 240 disease associations.
- UniProt accession: Q9H6D8; gene symbol FNDC4.
- Organism: Homo sapiens.
- Length: 234 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, total cholesterol measurement and C-reactive protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fibronectin type III domain-containing protein 4 |
|---|---|
| UniProt accession | Q9H6D8 |
| Gene | FNDC4 |
| Organism | Homo sapiens |
| Length | 234 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (240)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.13
- total cholesterol measurement · score 0.13
- C-reactive protein measurement · score 0.12
- serum albumin measurement · score 0.11
- IGF-1 measurement · score 0.10
- hepatocellular carcinoma · score 0.09
- type 2 diabetes mellitus · score 0.09
- low density lipoprotein cholesterol measurement · score 0.08
- hyperlipidemia · score 0.08
- phosphatidylcholine measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6D8-F1 | alphafold | PREDICTED | 69.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6D8.
Amino-acid sequence (234 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNDC4?
The strongest Open Targets associations for FNDC4 are triglyceride measurement, total cholesterol measurement, C-reactive protein measurement, serum albumin measurement and IGF-1 measurement.
How long is the FNDC4 protein?
The Homo sapiens FNDC4 protein (UniProt Q9H6D8) is 234 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6D8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6D8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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