Coiled-coil domain-containing protein 134 (CCDC134)
Homo sapiens — UniProt Q9H6E4
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 134 (CCDC134) is a protein from Homo sapiens identified by UniProt accession Q9H6E4, 229 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9H6E4; gene symbol CCDC134.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): osteogenesis imperfecta, IIA 22, Recurrent fractures and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 134 |
|---|---|
| UniProt accession | Q9H6E4 |
| Gene | CCDC134 |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- osteogenesis imperfecta, IIA 22 · score 0.46
- Recurrent fractures · score 0.33
- lean body mass · score 0.20
- body height · score 0.18
- mathematical ability · score 0.17
- birth weight · score 0.17
- forced expiratory volume · score 0.16
- fat body mass · score 0.16
- appendicular lean mass · score 0.15
- sitting height measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6E4-F1 | alphafold | PREDICTED | 82.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6E4.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC134?
The strongest Open Targets associations for CCDC134 are osteogenesis imperfecta, IIA 22, Recurrent fractures, lean body mass, body height and mathematical ability.
How long is the CCDC134 protein?
The Homo sapiens CCDC134 protein (UniProt Q9H6E4) is 229 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6E4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6E4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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