Coiled-coil domain-containing protein 86 (CCDC86)
Homo sapiens — UniProt Q9H6F5
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 86 (CCDC86) is a protein from Homo sapiens identified by UniProt accession Q9H6F5, 360 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q9H6F5; gene symbol CCDC86.
- Organism: Homo sapiens.
- Length: 360 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, diffuse large B-cell lymphoma and lymphoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 86 |
|---|---|
| UniProt accession | Q9H6F5 |
| Gene | CCDC86 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.11
- diffuse large B-cell lymphoma · score 0.08
- lymphoma · score 0.07
- Hodgkins lymphoma · score 0.05
- classic Hodgkin lymphoma · score 0.05
- severe combined immunodeficiency due to CARD11 deficiency · score 0.05
- reticular dysgenesis · score 0.05
- Okt4 epitope deficiency · score 0.05
- Waldenstrom macroglobulinemia · score 0.05
- immunodeficiency 18 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6F5-F1 | alphafold | PREDICTED | 61.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6F5.
Amino-acid sequence (360 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC86?
The strongest Open Targets associations for CCDC86 are neurofibrillary tangles measurement, diffuse large B-cell lymphoma, lymphoma, Hodgkins lymphoma and classic Hodgkin lymphoma.
How long is the CCDC86 protein?
The Homo sapiens CCDC86 protein (UniProt Q9H6F5) is 360 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6F5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6F5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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