Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 (CSTPP1)
Homo sapiens — UniProt Q9H6J7
Data last refreshed: (UniProt release unknown)
Key facts
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 (CSTPP1) is a protein from Homo sapiens identified by UniProt accession Q9H6J7, 331 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9H6J7; gene symbol CSTPP1.
- Organism: Homo sapiens.
- Length: 331 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, heel bone mineral density and feeling "fed-up" measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 |
|---|---|
| UniProt accession | Q9H6J7 |
| Gene | CSTPP1 |
| Organism | Homo sapiens |
| Length | 331 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.21
- heel bone mineral density · score 0.20
- feeling "fed-up" measurement · score 0.17
- self reported educational attainment · score 0.17
- blood protein measurement · score 0.16
- intraocular pressure measurement · score 0.12
- acne · score 0.12
- attention deficit hyperactivity disorder · score 0.12
- antisocial behaviour measurement · score 0.12
- substance abuse · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6J7-F1 | alphafold | PREDICTED | 80.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6J7.
Amino-acid sequence (331 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSTPP1?
The strongest Open Targets associations for CSTPP1 are high density lipoprotein cholesterol measurement, heel bone mineral density, feeling "fed-up" measurement, self reported educational attainment and blood protein measurement.
How long is the CSTPP1 protein?
The Homo sapiens CSTPP1 protein (UniProt Q9H6J7) is 331 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6J7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6J7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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