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Proline-rich protein 36 (PRR36)

Homo sapiens — UniProt Q9H6K5

Gene: PRR36Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Proline-rich protein 36 (PRR36) is a protein from Homo sapiens identified by UniProt accession Q9H6K5, 1346 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

  • UniProt accession: Q9H6K5; gene symbol PRR36.
  • Organism: Homo sapiens.
  • Length: 1346 amino acids.
  • Top disease associations (Open Targets): serum alanine aminotransferase measurement, base metabolic rate measurement and whole body water mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProline-rich protein 36
UniProt accessionQ9H6K5
GenePRR36
OrganismHomo sapiens
Length1346 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (16)

Diseases linked to this target (Open Targets).

  • serum alanine aminotransferase measurement · score 0.10
  • base metabolic rate measurement · score 0.07
  • whole body water mass · score 0.04
  • colorectal adenocarcinoma · score 0.03
  • C-reactive protein measurement · score 0.03
  • papillary thyroid carcinoma · score 0.03
  • colorectal cancer · score 0.01
  • Alzheimer disease · score 0.01
  • schizophrenia · score 0.01
  • Colon Sessile Serrated Adenoma/Polyp · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H6K5-F1alphafoldPREDICTED42.26—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6K5.

Amino-acid sequence (1346 residues)

MDNKRDKAKA GAAARTPAAR APGLLTPRPP GSPRPPPPVT PAALRVLGAA GAVGRKPLAE RAGGIGGATI PESAPRAGPT RSAGTSSRNP ASRPPASGRG ERAPPAKNTS PGPVSSPGRA SGTTRPGPLG QKGLRISAEE TVARGKATEA PKRSALSAGA RRDTSGPTPG TPSPAMARRS RAAGTEVGLP RPAPSARPRP PTEGPRKSVS SASEHSTTEP SPAARRRPSA GGGLQRPASR SLSSSATPLS SPARSGPSAR GTPRAPAHPS QPKPKGLQAL RPPQVTPPRK DAAPALGPLS SSPLATPSPS GTKARPVPPP DNAATPLPAT LPPSPPVTPP PPAALQSQAP PTLPATPHSS SLTCQLATPL PLAPPSPSAP PSLQTLPSPP ATPPSQVPPT QLIMSFPEAG VSSLATAAFV ASVSPSVSSP LQSMPPTQAN PALPSLPTLL SPLATPPLSA MSPLQGPVSP ATSLGNSAFP LAALPQPGLS ALTTPPPQAS PSPSPPSLQA TPHTLATLPL QDSPLLATLP LQASPSPLTT VSLQDPPLVS PSLLASPPLQ APPHPQAPPS MTTPPMQAPP SLQTIPPIQV PHSLTSPSLQ APPSPLALSS LQATTSLGSP TLQATHSFLT MSPRQTQASL ISPSRPASTP PDSPPLQAPL SLPASPPLQT SLSPAVSPLS SPLTIHPLQA LSSLASHSPQ APLSSLIMPP LETQSSLAPP SLQTPPASLT TPPLENLPSL APPPLQTASA PLTTPPLENL PSLAPPPLQT ASAPLTTPHL ETPPCPAPCP LQAPPSPLTT PPPETPSSIA TPPPQAPPAL ASPPLQGLPS PPLSPLATPP PQAPPALALP PLQAPPSPPA SPPLSPLATP SPQAPNALAV HLLQAPFSPP PSPPVQAPFS PPASPPVSPS ATPPSQAPPS LAAPPLQVPP SPPASPPMSP SATPPPQAPP PLAAPPLQVP PSPPASPPMS PSATPPPRVP PLLAAPPLQV PPSPPASLPM SPLAKPPPQA PPALATPPLQ ALPSPPASFP GQAPFSPSAS LPMSPLATPP PQAPPVLAAP LLQVPPSPPA SPTLQAPRRP PTPGPDTSVS GPRLTLALAP GPPPPPSRSP SSTLSGPDLA GHSSSATSTP EELRGYDSGP EGGAAASPPP DAELAACHPA AWSRGPAPPL AFRGAPGAPL PWPPATGPGS ADGLCTIYET EGPESATPAP GALDPGPSPG TSGGKAAAGA GAGASSRSPK QARLGELPLG ALQASVVQHL LSRTLLLAAA EGAAGGSGGG PGGAEGGGVT GGARAALSDA ELGRWAELLS PLDESRASIT SVTSFSPDDV ASPQGDWTVV EVETFH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PRR36?

The strongest Open Targets associations for PRR36 are serum alanine aminotransferase measurement, base metabolic rate measurement, whole body water mass, colorectal adenocarcinoma and C-reactive protein measurement.

How long is the PRR36 protein?

The Homo sapiens PRR36 protein (UniProt Q9H6K5) is 1346 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H6K5
GenePRR36
OrganismHomo sapiens
Length1346
Binders0
Diseases16
View on UniProt