Threonine aspartase 1 (TASP1)
Homo sapiens — UniProt Q9H6P5
Data last refreshed: (UniProt release unknown)
Key facts
Threonine aspartase 1 (TASP1) is a protein from Homo sapiens identified by UniProt accession Q9H6P5, 420 residues long. MolForge cross-references it against 0 known binders and 207 disease associations.
- UniProt accession: Q9H6P5; gene symbol TASP1.
- Organism: Homo sapiens.
- Length: 420 amino acids.
- Top disease associations (Open Targets): Suleiman-El-Hattab syndrome, Global developmental delay and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Threonine aspartase 1 |
|---|---|
| UniProt accession | Q9H6P5 |
| Gene | TASP1 |
| Organism | Homo sapiens |
| Length | 420 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (207)
Diseases linked to this target (Open Targets).
- Suleiman-El-Hattab syndrome · score 0.62
- Global developmental delay · score 0.43
- protein measurement · score 0.41
- Neurodevelopmental disorder · score 0.37
- FEV/FVC ratio · score 0.36
- Abnormal facial shape · score 0.33
- Happy demeanor · score 0.33
- peak expiratory flow · score 0.31
- developmental disability · score 0.27
- multiple congenital anomalies/dysmorphic syndrome-intellectual disability · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6P5-F1 | alphafold | PREDICTED | 86.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6P5.
Amino-acid sequence (420 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TASP1?
The strongest Open Targets associations for TASP1 are Suleiman-El-Hattab syndrome, Global developmental delay, protein measurement, Neurodevelopmental disorder and FEV/FVC ratio.
How long is the TASP1 protein?
The Homo sapiens TASP1 protein (UniProt Q9H6P5) is 420 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6P5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6P5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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