Cytosolic iron-sulfur assembly component 3 (CIAO3)
Homo sapiens — UniProt Q9H6Q4
Data last refreshed: (UniProt release unknown)
Key facts
Cytosolic iron-sulfur assembly component 3 (CIAO3) is a protein from Homo sapiens identified by UniProt accession Q9H6Q4, 476 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9H6Q4; gene symbol CIAO3.
- Organism: Homo sapiens.
- Length: 476 amino acids.
- Top disease associations (Open Targets): body height, lean body mass and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytosolic iron-sulfur assembly component 3 |
|---|---|
| UniProt accession | Q9H6Q4 |
| Gene | CIAO3 |
| Organism | Homo sapiens |
| Length | 476 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- body height · score 0.25
- lean body mass · score 0.24
- appendicular lean mass · score 0.23
- BMI-adjusted hip circumference · score 0.21
- fat body mass · score 0.19
- body weight · score 0.16
- BMI-adjusted waist circumference · score 0.16
- vital capacity · score 0.16
- base metabolic rate measurement · score 0.16
- whole body water mass · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6Q4-F1 | alphafold | PREDICTED | 85.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6Q4.
Amino-acid sequence (476 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CIAO3?
The strongest Open Targets associations for CIAO3 are body height, lean body mass, appendicular lean mass, BMI-adjusted hip circumference and fat body mass.
How long is the CIAO3 protein?
The Homo sapiens CIAO3 protein (UniProt Q9H6Q4) is 476 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6Q4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6Q4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.