ATP-dependent RNA helicase DHX33 (DHX33)
Homo sapiens — UniProt Q9H6R0
Data last refreshed: (UniProt release unknown)
Key facts
ATP-dependent RNA helicase DHX33 (DHX33) is a protein from Homo sapiens identified by UniProt accession Q9H6R0, 707 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9H6R0; gene symbol DHX33.
- Organism: Homo sapiens.
- Length: 707 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, bone density and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-dependent RNA helicase DHX33 |
|---|---|
| UniProt accession | Q9H6R0 |
| Gene | DHX33 |
| Organism | Homo sapiens |
| Length | 707 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- bone density · score 0.13
- urate measurement · score 0.13
- sarcoma · score 0.05
- platelet component distribution width · score 0.04
- cancer · score 0.04
- monocyte count · score 0.03
- hip bone size · score 0.03
- hip bone mineral density · score 0.02
- hematocrit · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6R0-F1 | alphafold | PREDICTED | 85.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6R0.
Amino-acid sequence (707 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DHX33?
The strongest Open Targets associations for DHX33 are neurodegenerative disease, bone density, urate measurement, sarcoma and platelet component distribution width.
How long is the DHX33 protein?
The Homo sapiens DHX33 protein (UniProt Q9H6R0) is 707 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6R0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6R0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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