Nucleolar protein 6 (NOL6)
Homo sapiens — UniProt Q9H6R4
Data last refreshed: (UniProt release unknown)
Key facts
Nucleolar protein 6 (NOL6) is a protein from Homo sapiens identified by UniProt accession Q9H6R4, 1146 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9H6R4; gene symbol NOL6.
- Organism: Homo sapiens.
- Length: 1146 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, endometrial cancer and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleolar protein 6 |
|---|---|
| UniProt accession | Q9H6R4 |
| Gene | NOL6 |
| Organism | Homo sapiens |
| Length | 1146 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.12
- endometrial cancer · score 0.10
- hepatocellular carcinoma · score 0.05
- gonorrhea · score 0.02
- infect · score 0.01
- infection · score 0.01
- neoplasm · score 0.01
- bacterial disease · score 0.01
- cancer · score 0.00
- non-functioning pituitary adenoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6R4-F1 | alphafold | PREDICTED | 88.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6R4.
Amino-acid sequence (1146 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOL6?
The strongest Open Targets associations for NOL6 are neurodegenerative disease, endometrial cancer, hepatocellular carcinoma, gonorrhea and infect.
How long is the NOL6 protein?
The Homo sapiens NOL6 protein (UniProt Q9H6R4) is 1146 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6R4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6R4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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