Palmitoyltransferase ZDHHC6 (ZDHHC6)
Homo sapiens — UniProt Q9H6R6
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC6 (ZDHHC6) is a protein from Homo sapiens identified by UniProt accession Q9H6R6, 413 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9H6R6; gene symbol ZDHHC6.
- Organism: Homo sapiens.
- Length: 413 amino acids.
- Top disease associations (Open Targets): apolipoprotein A 1 measurement, aspartate aminotransferase measurement and basophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC6 |
|---|---|
| UniProt accession | Q9H6R6 |
| Gene | ZDHHC6 |
| Organism | Homo sapiens |
| Length | 413 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.20
- aspartate aminotransferase measurement · score 0.17
- basophil percentage of leukocytes · score 0.13
- triglyceride measurement · score 0.13
- platelet count · score 0.12
- basophil count · score 0.12
- colorectal cancer · score 0.12
- total cholesterol measurement · score 0.11
- colorectal adenoma · score 0.08
- smoking status measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6R6-F1 | alphafold | PREDICTED | 86.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6R6.
Amino-acid sequence (413 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC6?
The strongest Open Targets associations for ZDHHC6 are apolipoprotein A 1 measurement, aspartate aminotransferase measurement, basophil percentage of leukocytes, triglyceride measurement and platelet count.
How long is the ZDHHC6 protein?
The Homo sapiens ZDHHC6 protein (UniProt Q9H6R6) is 413 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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