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WD repeat and coiled-coil-containing protein (WDCP)

Homo sapiens — UniProt Q9H6R7

Gene: WDCPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

WD repeat and coiled-coil-containing protein (WDCP) is a protein from Homo sapiens identified by UniProt accession Q9H6R7, 721 residues long. MolForge cross-references it against 0 known binders and 128 disease associations.

  • UniProt accession: Q9H6R7; gene symbol WDCP.
  • Organism: Homo sapiens.
  • Length: 721 amino acids.
  • Top disease associations (Open Targets): cancer, colorectal adenocarcinoma and lung carcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameWD repeat and coiled-coil-containing protein
UniProt accessionQ9H6R7
GeneWDCP
OrganismHomo sapiens
Length721 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (128)

Diseases linked to this target (Open Targets).

  • cancer · score 0.46
  • colorectal adenocarcinoma · score 0.28
  • lung carcinoma · score 0.19
  • gastric carcinoma · score 0.18
  • oral squamous cell carcinoma · score 0.18
  • acute myeloid leukemia · score 0.18
  • hepatocellular carcinoma · score 0.18
  • clear cell renal carcinoma · score 0.18
  • breast carcinoma · score 0.18
  • head and neck squamous cell carcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9H6R7-F1alphafoldPREDICTED67.89—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6R7.

Amino-acid sequence (721 residues)

MELGKGKLLR TGLNALHQAV HPIHGLAWTD GNQVVLTDLR LHSGEVKFGD SKVIGQFECV CGLSWAPPVA DDTPVLLAVQ HEKHVTVWQL CPSPMESSKW LTSQTCEIRG SLPILPQGCV WHPKCAILTV LTAQDVSIFP NVHSDDSQVK ADINTQGRIH CACWTQDGLR LVVAVGSSLH SYIWDSAQKT LHRCSSCLVF DVDSHVCSIT ATVDSQVAIA TELPLDKICG LNASETFNIP PNSKDMTPYA LPVIGEVRSM DKEATDSETN SEVSVSSSYL EPLDLTHIHF NQHKSEGNSL ICLRKKDYLT GTGQDSSHLV LVTFKKAVTM TRKVTIPGIL VPDLIAFNLK AHVVAVASNT CNIILIYSVI PSSVPNIQQI RLENTERPKG ICFLTDQLLL ILVGKQKLTD TTFLPSSKSD QYAISLIVRE IMLEEEPSIT SGESQTTYST FSAPLNKANR KKLIESLSPD FCHQNKGLLL TVNTSSQNGR PGRTLIKEIQ SPLSSICDGS IALDAEPVTQ PASLPRHSST PDHTSTLEPP RLPQRKNLQS EKETYQLSKE VEILSRNLVE MQRCLSELTN RLHNGKKSSS VYPLSQDLPY VHIIYQKPYY LGPVVEKRAV LLCDGKLRLS TVQQTFGLSL IEMLHDSHWI LLSADSEGFI PLTFTATQEI IIRDGSLSRS DVFRDSFSHS PGAVSSLKVF TGLAAPSLDT TGCCNHVDGM A

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with WDCP?

The strongest Open Targets associations for WDCP are cancer, colorectal adenocarcinoma, lung carcinoma, gastric carcinoma and oral squamous cell carcinoma.

How long is the WDCP protein?

The Homo sapiens WDCP protein (UniProt Q9H6R7) is 721 amino acids long.

Browse: Targets: W · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9H6R7
GeneWDCP
OrganismHomo sapiens
Length721
Binders0
Diseases128
View on UniProt