5-azacytidine-induced protein 2 (AZI2)
Homo sapiens — UniProt Q9H6S1
Data last refreshed: (UniProt release unknown)
Key facts
5-azacytidine-induced protein 2 (AZI2) is a protein from Homo sapiens identified by UniProt accession Q9H6S1, 392 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9H6S1; gene symbol AZI2.
- Organism: Homo sapiens.
- Length: 392 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lymphocyte count and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 5-azacytidine-induced protein 2 |
|---|---|
| UniProt accession | Q9H6S1 |
| Gene | AZI2 |
| Organism | Homo sapiens |
| Length | 392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- lymphocyte count · score 0.16
- Red cell distribution width · score 0.15
- lymphocyte percentage of leukocytes · score 0.12
- platelet-to-lymphocyte ratio · score 0.11
- multiple sclerosis · score 0.09
- systemic lupus erythematosus · score 0.08
- Epstein Barr virus nuclear antigen 1 IgG measurement · score 0.06
- mathematical ability · score 0.05
- cortical surface area measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6S1-F1 | alphafold | PREDICTED | 68.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6S1.
Amino-acid sequence (392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AZI2?
The strongest Open Targets associations for AZI2 are neurodegenerative disease, lymphocyte count, Red cell distribution width, lymphocyte percentage of leukocytes and platelet-to-lymphocyte ratio.
How long is the AZI2 protein?
The Homo sapiens AZI2 protein (UniProt Q9H6S1) is 392 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6S1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6S1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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