Anthrax toxin receptor 1 (ANTXR1)
Homo sapiens — UniProt Q9H6X2
Data last refreshed: (UniProt release unknown)
Key facts
Anthrax toxin receptor 1 (ANTXR1) is a protein from Homo sapiens identified by UniProt accession Q9H6X2, 564 residues long. MolForge cross-references it against 0 known binders and 272 disease associations.
- UniProt accession: Q9H6X2; gene symbol ANTXR1.
- Organism: Homo sapiens.
- Length: 564 amino acids.
- Top disease associations (Open Targets): GAPO syndrome, anthrax infection and Abnormality of the skeletal system.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anthrax toxin receptor 1 |
|---|---|
| UniProt accession | Q9H6X2 |
| Gene | ANTXR1 |
| Organism | Homo sapiens |
| Length | 564 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (272)
Diseases linked to this target (Open Targets).
- GAPO syndrome · score 0.72
- anthrax infection · score 0.55
- Abnormality of the skeletal system · score 0.55
- body height · score 0.49
- intraocular pressure measurement · score 0.46
- capillary infantile hemangioma · score 0.44
- FEV/FVC ratio · score 0.37
- vital capacity · score 0.33
- BMI-adjusted hip circumference · score 0.31
- glaucoma · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6X2-F1 | alphafold | PREDICTED | 72.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6X2.
Amino-acid sequence (564 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANTXR1?
The strongest Open Targets associations for ANTXR1 are GAPO syndrome, anthrax infection, Abnormality of the skeletal system, body height and intraocular pressure measurement.
How long is the ANTXR1 protein?
The Homo sapiens ANTXR1 protein (UniProt Q9H6X2) is 564 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6X2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6X2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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