Transmembrane protein 134 (TMEM134)
Homo sapiens — UniProt Q9H6X4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 134 (TMEM134) is a protein from Homo sapiens identified by UniProt accession Q9H6X4, 195 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9H6X4; gene symbol TMEM134.
- Organism: Homo sapiens.
- Length: 195 amino acids.
- Top disease associations (Open Targets): eosinophil percentage of leukocytes, mean corpuscular volume and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 134 |
|---|---|
| UniProt accession | Q9H6X4 |
| Gene | TMEM134 |
| Organism | Homo sapiens |
| Length | 195 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- eosinophil percentage of leukocytes · score 0.09
- mean corpuscular volume · score 0.06
- mean corpuscular hemoglobin · score 0.05
- body height · score 0.03
- mean corpuscular hemoglobin concentration · score 0.03
- acute myeloid leukemia · score 0.03
- urate measurement · score 0.02
- mean platelet volume · score 0.02
- Obesity · score 0.02
- BMI-adjusted waist circumference · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6X4-F1 | alphafold | PREDICTED | 58.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6X4.
Amino-acid sequence (195 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM134?
The strongest Open Targets associations for TMEM134 are eosinophil percentage of leukocytes, mean corpuscular volume, mean corpuscular hemoglobin, body height and mean corpuscular hemoglobin concentration.
How long is the TMEM134 protein?
The Homo sapiens TMEM134 protein (UniProt Q9H6X4) is 195 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6X4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6X4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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