WD repeat-containing protein 55 (WDR55)
Homo sapiens — UniProt Q9H6Y2
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 55 (WDR55) is a protein from Homo sapiens identified by UniProt accession Q9H6Y2, 383 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9H6Y2; gene symbol WDR55.
- Organism: Homo sapiens.
- Length: 383 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, aspartate aminotransferase measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 55 |
|---|---|
| UniProt accession | Q9H6Y2 |
| Gene | WDR55 |
| Organism | Homo sapiens |
| Length | 383 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- aspartate aminotransferase measurement · score 0.22
- monocyte count · score 0.19
- systolic blood pressure · score 0.12
- bipolar I disorder · score 0.11
- pulse pressure measurement · score 0.07
- vital capacity · score 0.07
- blood protein measurement · score 0.07
- forced expiratory volume · score 0.06
- depressive symptom measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6Y2-F1 | alphafold | PREDICTED | 87.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6Y2.
Amino-acid sequence (383 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR55?
The strongest Open Targets associations for WDR55 are neurodegenerative disease, aspartate aminotransferase measurement, monocyte count, systolic blood pressure and bipolar I disorder.
How long is the WDR55 protein?
The Homo sapiens WDR55 protein (UniProt Q9H6Y2) is 383 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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