E3 ubiquitin-protein ligase RNF167 (RNF167)
Homo sapiens — UniProt Q9H6Y7
Data last refreshed: (UniProt release unknown)
Key facts
E3 ubiquitin-protein ligase RNF167 (RNF167) is a protein from Homo sapiens identified by UniProt accession Q9H6Y7, 350 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9H6Y7; gene symbol RNF167.
- Organism: Homo sapiens.
- Length: 350 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, calcium measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | E3 ubiquitin-protein ligase RNF167 |
|---|---|
| UniProt accession | Q9H6Y7 |
| Gene | RNF167 |
| Organism | Homo sapiens |
| Length | 350 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- calcium measurement · score 0.14
- mean platelet volume · score 0.10
- platelet count · score 0.09
- blood metabolite measurement · score 0.08
- platelet component distribution width · score 0.04
- mathematical ability · score 0.04
- platelet crit · score 0.04
- erythrocyte count · score 0.03
- intraocular pressure measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6Y7-F1 | alphafold | PREDICTED | 78.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6Y7.
Amino-acid sequence (350 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF167?
The strongest Open Targets associations for RNF167 are neurodegenerative disease, calcium measurement, mean platelet volume, platelet count and blood metabolite measurement.
How long is the RNF167 protein?
The Homo sapiens RNF167 protein (UniProt Q9H6Y7) is 350 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6Y7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6Y7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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