Ran-binding protein 3 (RANBP3)
Homo sapiens — UniProt Q9H6Z4
Data last refreshed: (UniProt release unknown)
Key facts
Ran-binding protein 3 (RANBP3) is a protein from Homo sapiens identified by UniProt accession Q9H6Z4, 567 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9H6Z4; gene symbol RANBP3.
- Organism: Homo sapiens.
- Length: 567 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ran-binding protein 3 |
|---|---|
| UniProt accession | Q9H6Z4 |
| Gene | RANBP3 |
| Organism | Homo sapiens |
| Length | 567 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- lysosomal storage disease · score 0.42
- Parkinson disease · score 0.42
- Alzheimer disease · score 0.42
- multiple sclerosis · score 0.42
- balding measurement · score 0.13
- vital capacity · score 0.13
- forced expiratory volume · score 0.11
- monocyte percentage of leukocytes · score 0.07
- chronic myelogenous leukemia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H6Z4-F1 | alphafold | PREDICTED | 61.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H6Z4.
Amino-acid sequence (567 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RANBP3?
The strongest Open Targets associations for RANBP3 are neurodegenerative disease, lysosomal storage disease, Parkinson disease, Alzheimer disease and multiple sclerosis.
How long is the RANBP3 protein?
The Homo sapiens RANBP3 protein (UniProt Q9H6Z4) is 567 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H6Z4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H6Z4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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