Protein associated with UVRAG as autophagy enhancer (RUBCNL)
Homo sapiens — UniProt Q9H714
Data last refreshed: (UniProt release unknown)
Key facts
Protein associated with UVRAG as autophagy enhancer (RUBCNL) is a protein from Homo sapiens identified by UniProt accession Q9H714, 662 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q9H714; gene symbol RUBCNL.
- Organism: Homo sapiens.
- Length: 662 amino acids.
- Top disease associations (Open Targets): prostate cancer, prostate carcinoma and Familial prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein associated with UVRAG as autophagy enhancer |
|---|---|
| UniProt accession | Q9H714 |
| Gene | RUBCNL |
| Organism | Homo sapiens |
| Length | 662 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- protein measurement · score 0.10
- body height · score 0.07
- adolescent idiopathic scoliosis · score 0.02
- axial length measurement · score 0.01
- cancer · score 0.01
- ulcerative colitis · score 0.01
- cervical intraepithelial neoplasia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H714-F1 | alphafold | PREDICTED | 60.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H714.
Amino-acid sequence (662 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RUBCNL?
The strongest Open Targets associations for RUBCNL are prostate cancer, prostate carcinoma, Familial prostate cancer, protein measurement and body height.
How long is the RUBCNL protein?
The Homo sapiens RUBCNL protein (UniProt Q9H714) is 662 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H714 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H714 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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