Leucine-rich repeat-containing protein 19 (LRRC19)
Homo sapiens — UniProt Q9H756
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 19 (LRRC19) is a protein from Homo sapiens identified by UniProt accession Q9H756, 370 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9H756; gene symbol LRRC19.
- Organism: Homo sapiens.
- Length: 370 amino acids.
- Top disease associations (Open Targets): colitis, wellbeing measurement and Immunodeficiency due to a late component of complements deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 19 |
|---|---|
| UniProt accession | Q9H756 |
| Gene | LRRC19 |
| Organism | Homo sapiens |
| Length | 370 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- colitis · score 0.09
- wellbeing measurement · score 0.06
- Immunodeficiency due to a late component of complements deficiency · score 0.06
- Barrett's esophagus · score 0.05
- immunodeficiency 35 · score 0.05
- actinic keratosis · score 0.05
- depressive symptom measurement · score 0.05
- neuroticism measurement · score 0.05
- isolated agammaglobulinemia · score 0.05
- sebaceous of Jadassohn nevus · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H756-F1 | alphafold | PREDICTED | 74.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H756.
Amino-acid sequence (370 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC19?
The strongest Open Targets associations for LRRC19 are colitis, wellbeing measurement, Immunodeficiency due to a late component of complements deficiency, Barrett's esophagus and immunodeficiency 35.
How long is the LRRC19 protein?
The Homo sapiens LRRC19 protein (UniProt Q9H756) is 370 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H756 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H756 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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