Ribosome production factor 2 homolog (RPF2)
Homo sapiens — UniProt Q9H7B2
Data last refreshed: (UniProt release unknown)
Key facts
Ribosome production factor 2 homolog (RPF2) is a protein from Homo sapiens identified by UniProt accession Q9H7B2, 306 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9H7B2; gene symbol RPF2.
- Organism: Homo sapiens.
- Length: 306 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosome production factor 2 homolog |
|---|---|
| UniProt accession | Q9H7B2 |
| Gene | RPF2 |
| Organism | Homo sapiens |
| Length | 306 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- self reported educational attainment · score 0.05
- brain measurement · score 0.04
- neurofibrillary tangles measurement · score 0.04
- hepatocellular carcinoma · score 0.02
- neoplasm · score 0.01
- infect · score 0.00
- infection · score 0.00
- lung adenocarcinoma · score 0.00
- cervical squamous cell carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7B2-F1 | alphafold | PREDICTED | 90.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7B2.
Amino-acid sequence (306 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPF2?
The strongest Open Targets associations for RPF2 are neurodegenerative disease, self reported educational attainment, brain measurement, neurofibrillary tangles measurement and hepatocellular carcinoma.
How long is the RPF2 protein?
The Homo sapiens RPF2 protein (UniProt Q9H7B2) is 306 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7B2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7B2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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