Syncoilin (SYNC)
Homo sapiens — UniProt Q9H7C4
Data last refreshed: (UniProt release unknown)
Key facts
Syncoilin (SYNC) is a protein from Homo sapiens identified by UniProt accession Q9H7C4, 482 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9H7C4; gene symbol SYNC.
- Organism: Homo sapiens.
- Length: 482 amino acids.
- Top disease associations (Open Targets): drug use measurement, ependymoma and ovarian carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syncoilin |
|---|---|
| UniProt accession | Q9H7C4 |
| Gene | SYNC |
| Organism | Homo sapiens |
| Length | 482 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- drug use measurement · score 0.04
- ependymoma · score 0.02
- ovarian carcinoma · score 0.02
- colorectal cancer · score 0.02
- neoplasm · score 0.02
- non-small cell lung carcinoma · score 0.02
- Tetralogy of Fallot · score 0.02
- glioblastoma multiforme · score 0.01
- hypertrophic cardiomyopathy · score 0.01
- Duchenne muscular dystrophy · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9H7C4-F1 | alphafold | PREDICTED | 72.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9H7C4.
Amino-acid sequence (482 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYNC?
The strongest Open Targets associations for SYNC are drug use measurement, ependymoma, ovarian carcinoma, colorectal cancer and neoplasm.
How long is the SYNC protein?
The Homo sapiens SYNC protein (UniProt Q9H7C4) is 482 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9H7C4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9H7C4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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